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Saturday, September 3, 2011


CANCER PREVENTION

Over the past four years, apple consumption has been linked with
reduced cancer risk in several studies. A 2001 Mayo Clinic study
indicated that quercetin, a flavonoid abundant in apples, helps prevent
the growth of prostate cancer cells. A Cornell University study
indicated phytochemicals in the skin of an apple inhibited the
reproduction of colon cancer cells by 43 percent. The National Cancer
Institute has reported that foods containing flavonoids like those
found in apples may reduce the risk of lung cancer by as much as 50
percent.

?
Carcinogenesis (March, 2001)

? Nature (June, 2000)

? Journal of the National Cancer Institute (January, 2000)

HEALTHY LUNGS

Two recent British studies indicated that eating apples
can improve lung health. A study of Welsh men indicated that people who
ate at least five apples per week experience better lung function.
Researchers at the University of Nottingham reported that those who ate
five apples per week also had a lower risk for respiratory disease. In
the Netherlands
at the University of Groningen, apples were singled out as a fruit that
could cut smokers' risk of COPD (chronic obstructive pulmonary disease)
in half. Scientists believe antioxidants found in apples may ward off
disease by countering oxygen's damaging effects on the body.

?
American Thoracic Society Meeting (May, 2001)

?Thorax (January, 2000)

HEART DISEASE & STROKE PREVENTION

A Finnish study published in 1996 showed that people who
eat a diet rich in flavonoids have a lower incidence of heart disease.
Other studies indicate that flavonoids may help prevent strokes.

?The British Medical
Journal
(1996)

WEIGHT
LOSS

Apples are a delicious source of dietary fiber, and
dietary fiber helps aid digestion and promotes weight loss. A medium
apple contains about five grams of fiber, more than most cereals. Also,
apples contain almost zero fat and cholesterol, so they are a delicious
snack and dessert food that's good for you.

UC-DAVIS:
APPLES ARE HEART-HEALTHY

Researchers at the University of
California-Davis
recently reported that apples and apple juice
may help protect arteries from harmful plaque build-up. In the first
study conducted in humans, adults who added two apples, or 12 ounces of
100% apple juice, to their daily diet demonstrated a significant
slowing of the cholesterol oxidation process that leads to plaque
build-up - thereby giving the body more time to rid itself of
cholesterol before it can cause harm.

AGE-RELATED MEMORY
IMPROVEMENT LINKED WITH CONSUMPTION OF APPLE PRODUCTS

New Study Finds Consuming Apple Juice Associated
With Brain Health In Older Animals

LOWELL,
MASS.
(January 19, 2006) ' "An apple a day" now has new meaning for
those who want to maintain mental dexterity as they age. New
research from the University of Massachusetts Lowell suggests that
consuming apple juice may protect against cell damage that contributes
to age-related memory loss, even in test animals that were not prone to
developing Alzheimer's disease and other dementias.

"This new
study suggests that eating and drinking apples and apple juice, in
conjunction with a balanced diet, can protect the brain from the
effects of oxidative stress ' and that we should eat such antioxidant-
rich foods," notes lead researcher Thomas B. Shea, Ph.D ., director of
the University of Massachusetts Lowell's Center for Cellular
Neurobiology and Neurodegeneration Research, whose study was just
published in the latest issue of the Journal of Alzheimer's Disease.
Although more research is needed, Shea is excited about these brain
health findings, which are encouraging for all individuals who are
interested in staying mentally sharp as they age.

Using a
well-established animal protocol, Shea and his research colleagues
assessed whether consumption of apple juice was protective against
oxidative brain damage in aging mice, damage that can lead to memory
loss. "These newer findings show that there is something in apples and
apple juice that protects brain cells in normal aging, much like the
protection we previously saw against Alzheimer-like
symptoms
," says Shea.

The
researchers evaluated adult and aged mice using a standard diet, a
nutrient-deficient diet, and a nutrient-deficient diet supplemented
with apple juice concentrate in drinking water. Although the
adult mice tested were not affected negatively by the deficient diets,
the aged mice were, which is consistent with normal aging due to
oxidative neurodegeneration. The effect on cognition among the aged
mice was measured through well-established maze tests, followed by an
examination of brain tissue. However, the aged mice who consumed
the diets supplemented with apple juice performed significantly better
on the maze tests and all had less oxidative brain damage than those on
the standard diet.

Supplementation
by apple juice fully protected the aged mice from the oxidative stress
caused by the nutrient-deficient diet. In addition, stronger
mental acuity resulted when the aged mice consumed the human equivalent
of 2-3 cups of apple juice or approximately 2-4 apples per day.
"We believe that this effect is due to the apple's naturally high level
of antioxidants," states Shea. Previous research with his
colleagues also determined that it is not the sugar and energy content
of the apple juice, but the antioxidant attributes of apple juice that
are responsible for the positive effects.

This
study was sponsored through an unrestricted grant by the U.S. Apple
Association and the Apple Products Research and Education Council.

The
research abstract can be found at

?University
of Massachusetts Lowell

US: STUDY LINKS APPLES TO REDUCED RISK OF HEART DISEASE
IN WOMEN

American Heart
Association
new recommendations support increased fruit,
vegetable consumption

Apples
may prove to be a winner when it comes to reducing the risk of heart
disease, says a new study of more than 34,000 women. In this study,
flavonoid-rich apples were found to be one of three foods (along with
red wine and pears) that decrease the risk of mortality for both
coronary heart disease (CHD) and cardiovascular disease (CVD) among
post-menopausal women, The findings were published in the March 2007 American Journal
of Clinical Nutrition
.

Women of all ages are encouraged to consume
more fruit and vegetables
, including apples and apple products,
for heart health. However, this study focused on postmenopausal woman,
a group becoming more aware of the risk for heart disease. Using a
government database that assesses the flavonoid-compound content of
foods, the researchers hypothesized that flavonoid intake (in general
and from specific foods), might be inversely associated with mortality
from CVD and CHD among the women in the study groupSubjects selected
for this research analysis were postmenopausal and part of the ongoing Iowa
Women”s Health Study, each of which has been monitored for dietary
intake and various health outcomes for nearly 20 years.

As a
result of the extensive analysis that considered what the women ate,
the types of cardiovascular- related diseases they experienced, and the
overall flavonoid content of an extensive list of foods, the
researchers concluded that consumption of apples, pears and red wine
were linked with the lowest risk for mortality related to both CHD and
CVD (not just one or the other).

“Flavonoids are compounds found in
small quantities in numerous plant foods, including fruits and
vegetables, tea, wine, nuts and seeds, and herbs and spices,” say the
university researchers from the University of Minnesota and the
University of Oslo (Norway) Earlier research has indicated that
flavonoids also have antioxidant properties that are linked to the
reduction of oxidation of the bad (LDL - low density lipoprotein)
cholesterol which have been linked in various ways with the development
of CVD. According to the government database cited in this paper,
apples contain a wide variety of flavonoid compounds.

The
researchers also believe this is the first prospective study of
postmenopausal women to report on the intake and impact of total and
specific flavonoid subclasses. They conclude, “Dietary intakes of
flavanones, anthocyanins, and certain foods rich in flavonoids were
associated with reduced risk of death due to CHD, CVD and all causes.”

The publication of this positive study for
apples
comes on the heels of updated heart disease prevention
guidelines for women just released by the American Heart
Association
in the February 20 issue of Circulation. As part of
their guidelines, AHA emphasizes that women increase their intake of
fruits and vegetables to help prevent heart disease over their
lifetime, not just to reduce short-term risk. Worldwide, cardiovascular
disease is the largest single cause of mortality among women,
accounting for one third of all deaths.

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